Reduces fatigue by using Andrographis paniculata: A Case of Multiple Sclerosis Patients

Multiple Sclerosis is an autoimmune disease that attacks the central nervous system, especially the brain, spinal cord, and the optic nerve. This is a long-term disease that is characterized by impaired balance, vision, muscle control and adjustment.

So, what are the symptoms of a disease related to oversight multiple sclerosis?

  • Impairment of vision, blurred vision, unfocused, and double vision
  • Numbness / numbness and tingling in the limbs and face
  • Prolonged pain, muscle stiffness, and spasms
  • Feeling tired suddenly and for no reason
  • Dizziness and vertigo
  • Balance problems

As normal adult early symptoms of feeling tired for no reason will reduce the effectiveness of work. Of course, this is a huge problem.

The latest Neurology research in Chile mention Andrographis paniculata can play a role in reducing fatigue in multiple sclerosis participants at the age of 18 – 50.

Let’s look briefly at the greatness of one of the herbs that come from South-East Asia. A. paniculata (well known as King of bitter) extracts have been used in autoimmune diseases and can exert anti-inflammatory effects. Many studies indicate that andrographolide, the main compound  in A. paniculata, is responsible for the reduction of innate and adaptive immune responses. On the other hand, the active compounds of A. paniculata have shown low toxicity, as reported by different clinical studies. The most common adverse event presented in some isolated cases is the development of mild skin rash, probably associated with andrographolide or its metabolites. It disappears upon withdrawal of the drug.

Andrographolide is an apolar compound of low molecular weight that crosses the blood-brain barrier and exerts neuroprotective effects.

A. paniculata treatment in Multiple Sclerosis patients shows a reduction in fatigue at one year. A. paniculata was safe and well tolerated, and no changes in clinical parameters were observed in the research.

Read more about our product Andrographis paniculata.

[1] Bertoglio, J. C., Baumgartner, R. Palma, E. Ciampi, C. Carcamo, D. D. Cáceres, G. Acosta-Jamett, J. L. Hancke and R. A. Burgos. 2016. Andrographis paniculata decreases fatigue in patients with relapsing-remitting multiple sclerosis: a 12-month double-blind placebo-controlled pilot study. BMC Neurology 16:77.

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